Monolaurin (Lauric Acid) 300mg 90 Capsules

• Monolaurin - Antivirus supplement to help fight colds, flu, shingles, herpes, Epstein-Barr Virus, chronic fatigue syndrome.
• May help protect the immune system from a range of infectious agents.
• No antibiotics - Does not destroy friendly bacteria.
• Monolaurin is good for both one-time and long-term preventative use.
• Extracted from coconut oil

WHAT IS MONOLAURIN
Monolaurin is an anti-microbial agent that protects the immune system from a range of infectious agents. Monolaurin is a glyceride ester derivative of lauric acid, a fatty acid found naturally in breast milk and certain vegetable oils.  This fatty acid has been used as a germicidal agent for centuries.  Lauric acid was originally discovered when microbiologists studied human breast milk to determine the antiviral substances which protected infants from microbial infections. It has been shown to protect newborns, whose immune systems are underdeveloped, from Respiratory Syncytial Virus (RSV) and other respiratory tract viruses (1,2).  Monolaurin was found to have even greater viral activity than lauric acid.
 

WHAT IS MONOLAURIN EFFECTIVE IN TREATING
In general, Monolaurin can help fight colds, flu, EBV, shingles, herpes, and chronic fatigue syndrome.

In studies performed at the Respiratory Virology Branch, Centers for Disease Control, Atlanta, Georgia, Monolaurin was found effective against 14 human RNA and DNA enveloped viruses in cell culture (3). These included influenza, RSV, Rubeola, Newcastle's, Coronavirus, Herpes Simplex types 1 & 2, Epstein-Barr Virus (EBV) and cytomegalovirus. (Monolaurin has no effect on naked viruses, such as polio, encephalitis virus, coxsachie, or pox viruses.) Monolaurin removed all measurable infectivity by disintegrating the virus envelope.

 
HOW CAN I PROTECT MYSELF DURING THE COLD AND FLU SEASON
Monolaurin serves as a valuable nutritional adjunct for people who feel that they are coming down with a cold or flu. Many physicians have developed their own clinical protocols in their cold and flu prevention program and recommend taking several capsules of Monolaurin on an empty stomach.

Monolaurin is not the type of nutritional supplement you have to take on a daily basis (although many people take it regularly for prevention purposes), but only when the need arises. If you have a fever or swollen lymph glands, it is always best to see a physician, but if you sense the early warning signs of the flu, like sniffles, sore skin and perhaps a scratchy throat, Monolaurin may offer the first line of defense.
 

ANTIBIOTICS, MONOLAURIN AND THE FLU
Antibiotics kill unwanted micro-organisms, but they also kill many friendly micro-organisms.  Monolaurin, on the other hand, does not appear to have an adverse effect on desirable digestive bacteria, but rather only on unwanted microorganisms. In addition Monolaurin can reduce the resistance of germs to antibiotics.

Frequent antibiotic use can lead to major disruptions in health and especially immune system function.  Antibiotic resistance, resulting from the over-use of prescription drugs, is one of the biggest problems facing the medical community today. Resistance is cumulative (and comes in part from antibiotics in our food supply). That's why it's important to consider starting with nutritional agents, such as Monolaurin, first. Uncomplicated flu, while unpleasant, is not life threatening and doesn't necessitate drug therapy. Nutritional physiologic agents, such as Monolaurin, may be a good first choice.
 

IS MONOLAURIN SAFE
Not only is Monolaurin included on the GRAS (Generally Recognized As Safe) list, but it may, by virtue of its source of origin, be safer than many other food supplements that are designed to boost the immune system. 

One of the safest substances known to man is breast milk. This is where the monoglyceride of lauric acid (Monolaurin) is found. When an infant is born, it is totally dependent on food factors in the mother's milk for immune protection. In analyzing the composition of human breast milk, medical researchers found lauric acid monoglycerides in high concentrations. Monolaurin is also found in coconut oil, butter, and heavy cream; only recently has it been isolated and purified. It is highly unusual in pharmacology to find chemicals that are toxic to lower forms of life (bacteria, fungi, and viruses) but non-toxic to man.
 

 Ingredients

Directions for Use

For those who feel as if they are coming down with a viral infection:

• 300 mg Capsules - 6 mg capsules of Monolaurin on an empty stomach, first thing in the morning, and for more severe cases, 6 more at night.

For those with a sensitive stomach, Monolaurin can be taken with food. The dose can be tapered off as symptoms decrease. Of course, you should always seek the advice of a physician if you have fever, pain or if symptoms persist.

Young children can also take Monolaurin at a reduced dose.  If you are giving Monolaurin to children (or adults) who have difficulty swallowing capsules, you can break them open and sprinkle the Monolaurin into something such as applesauce or yogurt. 

For Epstein-Bar Virus,  Herpes 1 & 2, or other chronic viral conditions:

• 300 mg Capsules - 6 capsules of Monolaurin when there is a flare-up
  and 2 capsules as a maintenance dose during dormant periods.

Sometimes the herpes virus can be activated by Monolaurin and then killed, resulting in a Herxheimer-like reaction.  Similar protocols have been used with the Epstein-Barr virus (closely resembling the herpes virus), which may be responsible for Chronic Fatigue and even MS (16, 17).

References

1. Isaacs CE. The antimicrobial function of milk lipids. Adv. Nutr. Res. 10:271-85, 2001.

2. Welsh JK, May JT. Anti-infective properties of breast milk. J. Pediatrics 94, 1-9, 1979.

3. Hierholzer JC and Kabara JJ. In vitro effects of Monolaurin compounds on enveloped RNA and DNA viruses. J. Food Safety 4:1, 1982.

4. Kabara JJ. Lipids as host-resistance factors of human milk. Nutr. Rev. 38:65, 1980.

5. Silver RK et al. Factors in human milk interfering with influenza-virus activities. Science 123:932-933, 1956.

6. Cohen SS. Strategy for the chemotherapy of infectious diseases. Science 197:431, 1977.

7. Dulbecco A. Interference with viral multi- plication. In: Virology, Dulbecco, A. and Ginsberg, H. edit, Harper & Row, Philadelphia, 1980.

8. Kabara JJ et al. Fatty acids and derivatives as antimicrobial agents. Antimicrob. Agents Chemother. 2:23, 1972.

9. Sands JA et al. Antiviral effects of fatty acids and derivatives. In: Pharmacological Effects of Lipids. Am. Oil Chem. Soc: Champaign, 1979;75.

10. Beuchat LA. Comparison of antiviral activities of potassium sorbate, sodium benzoate and glycerol and sucrose esters of fatty acids. Appi. Environ. Microbiol. 39:1178, 1980.

11. Sands J et al. Extreme sensitivity of enveloped viruses, including herpes simplex, to long chain unsaturated monoglycerides and alcohols. Antimicrobial Agents and Chemotherapy 15(1):67-73, 1979.

12. Kohn A. et al. Unsaturated free fatty acids inactivated animal envelope viruses. Arch. Virol. 66:301-306, 1980.

13. Ismail-Cassim, N et al. Inhibition of the uncoating of bovine enterovirus by short chain fatty acids. J. Gen. Virol. 71(10):2283-9, 1990.

14. Rabia S. et al. Inactivation of vesicular stomatitis virus by photosensitization following incubation with a pyrene-fatty acid. Febs. Let. 270(12):9-10, 1990.

15. Boddie RL and Nickerson SE. Evaluation of postmilking teat germicides containing Lauricidin, saturated fatty acids, and lactic acid. J. Dairy Sci. 75(6):1725-30, 1992.

16. Ascherio A., Munger K.L., Lenette E.T., Spiegelman D., Hernan M.A., Olek M.J., Hankinson S.E., and Hunter, D.J. Epstein-Barr virus antibodies and risk of multiple sclerosis: a prospective study. JAMA 286(24:3127-9, Dec. 26th, 2001.

17. Simmons A. Herpes virus and multiple sclerosis. Herpes 8(3):60-3, Nov. 2001.

© 2002 Ecological Formulas/Cardiovascular Research, Ltd.

Lauricidin
Technical information on Lauricidin® (monolaurin) for the Health Professional

The antiviral, antibacterial, and antiprotozoal properties of lauric acid and monolaurin have been recognized for nearly three decades by only a small number of researchers: their work, however, has resulted in 50 or more research papers an numerous U.S. and foreign patents. Prof. Dr. Jon J. Kabara performed the original seminal research in this area of fat research. Kabara (1968) first patented certain fatty acids (FAs) and their derivatives (e.g., monoglycerides (MGs) can have adverse effects on various microorganisms. While nontoxic and approved as a direct food additive by the FDA, monolaurin adversely affects bacteria, yeast, fungi, and enveloped viruses.

Kabara found that the properties that determine the anti-infective action of lipids are related to their structure: e.g., free fatty acids & monoglycerides. The monoglycerides are active; diglycerides and triglycerides are inactive. Of the saturated fatty acids, lauric acid has greater antiviral activity than either caprylic acid (C-8), capric acid (C-10), or myristic acid (C-14).

Fatty acids and monoglycerides produce their killing/inactivating effects by several mechanisms. An early postulated mechanism was the perturbing of the plasma membrane lipid bilayer. The antiviral action attributed to monolaurin is that of fluidizing the lipids and phospholipids in the envelope of the virus, causing the disintegration of the microbial membrane. More recent studies indicate that one antimicrobial effect in bacteria is related to monolaurin's interference with signal transduction/toxin formation (Projan et al 1994). Another antimicrobial effect in viruses is due to lauric acid's interference with virus assembly and viral maturation (Hornung et al 1994). The third mode of action may be on the immune system itself (Witcher et al, 1993).

Hierholzer and Kabara (1982) first reported the antiviral activity of the monoglyceride of lauric acid (monolaurin) on viruses that affect humans.. They showed virucidal effects of monolaurin on enveloped RNA and DNA viruses. This work was done at the Center for Disease Control of the U.S. Public Health Service. This study was carried out using selected virus prototypes or recognized representative strains of enveloped human viruses. All these viruses have a lipid membrane. The presence of a lipid membrane on viruses makes them especially vulnerable to lauric acid and its derivative monolaurin. These initial findings have been confirmed by many other studies.

Research has shown that enveloped viruses are inactivated by added fatty acids and monoglycerides in both human and bovine milk (Isaacs et al 1991). Others (Isaacs et al 1986, 1990, 1991, 1992; Thormar et al 1987) have confirmed Kabara's original statements concerning the effectiveness of monolaurin.

Some of the viruses inactivated by these lipids are the measles virus, herpes simplex virus (HSV-1 and -2), herpes family members (HIV, hepatitis C, vesicular, stomatitis virus (VSV), visna virus, and cytomegalovirus (CMV). Many of the pathogenic organisms reported to be inactivated by these antimicrobial lipids are those know to be responsible for opportunistic infections in HIV -positive individuals. For example, concurrent infection with cytomegalovirus is recognized as a serious complication for HIV positive individuals (Macallan et al 1993).

Thus, it would appear imperative to investigate the practical aspects and the potential benefit of a nutritional supplement such as monolaurin (Lauricidin) for microbial infected individuals. Until now few nutritionists in mainstream nutrition community seem to have recognized the added benefit of antimicrobial lipids in the support of infected patients. These antimicrobial fatty acids and their derivatives are essentially nontoxic to man. According to the published research, lauric acid is one of the best "inactivating" fatty acids, and its monoglyceride is even more effective than the fatty acid alone (Kabara 1978, Sands et al 1978, Fletcher et al 1985, Kabara 1985).

It should be emphasized that lauric acid cannot be taken orally because it is severally irritating. Lauricidin® on the other hand, a derivative of lauric acid chemically bonded to glycerol to form monolaurin, can be taken orally without any problem.
The lipid-coated (envelope) viruses, bacteria and other microorganisms are dependent on host lipids for their lipid constituents. The variability of fatty acids in the foods of individuals as well as the variability from de novo synthesis accounts for the variability of fatty acids in their membranes.

Monolaurin does not appear to have an adverse effect on desirable gut bacteria, but rather on only potentially pathogenic microorganisms. For example, Isaacs et al (1991) reported no inactivation of the common Esherichiacoli or Salmonella enteritidis by monolaurin, but major inactivation of Hemophilus influenza, Staphylococcus epidermis and Group B gram positive streptococcus.

The potentially pathogenic bacteria inactivated by monolaurin include Listeria monocytogenes, Staphylococcus aureus, Streptococcus agalactiae, Groups A, streptococci-gram-positive organisms, and some gram-negative organisms (Vibrio parahaemolyticus and Helicobacter pylori).

Decreased growth of Staphylococcus aureus and decreased production of toxic shock syndrome toxin-l was shown with monolaurin (Holland et al 1994). Monolaurin was 5000 times more inhibitory against Listeria monocytogenes than ethanol (Oh & Marshall 1993). In vitro monolaurin rapidly inactivate Helicobacter pylori. Of greater significance there appears to be very little development of resistance of the organism to the bactericidal effects (Petschow et al 1996) of these natural antimicrobials.

A number of fungi, yeast, and protozoa are also inactivated or killed by monolaurin. The fungi include several species of ringworm (Isaacs et al 1991). The yeast reported to be affected is Candida albicans (Isaacs et al 1991) The protozoan parasite Giardia lamblia is killed by monoglycerides from hydrolyzed human milk (Hemell et al 1986, Reiner et al 1986, Crouch et al 1991, Isaacs et al 1991).

Chlamydia trachomatis is inactivated by monolaurin (Bergsson et al 1998). Hydrogels containing monocaprin/monolaurin are potent in vitro inactivators of sexually transmitted viruses such as HSV-2 and HIV-1 and bacteria such as Neisserian gonorrhea (Thormar 1999).

Read more: http://www.aviva.ca/article.asp?articleid=13#ixzz1kmYL9F9Z

THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FDA. NOT INTENDED TO DIAGNOSE, TREAT OR CURE ANY DISEASE.

• Orders for products that are in stock are dispatched daily Monday – Friday.
• Orders placed before 3pm (CET) Monday – Friday will be dispatched the same day.
• Orders placed after 3pm (CET) Monday – Friday will be dispatched the next working day.
• As such, orders placed after 3pm (CET) on Friday will be dispatched the following Monday.
• Orders will not be dispatched on Bank Holidays (Netherlands) or Weekends.

Delivery

We have access to a variety of shipping options, provided by Deutsche Post, DPD and DHL Courier. You will select your delivery preference at the checkout when you place the order. We will endeavour to use your preferred delivery service wherever possible, while reserving the right to use an alternative courier of our choice as we deem necessary, this would always be a delivery upgrade, and never a downgrade.

As standard, we are only using delivery services that include tracking and insurance against damage/loss. This means if your parcel doesn’t arrive, or is damaged on arrival, you are entitled to a refund/replacement. All you need to do is send us some pictures of the damage. If you prefer to use a cheaper delivery service without tracking and insurance we can provide this for you by request, but if the parcel doesn’t arrive, or is damaged on arrival then you are not entitled to any refund/replacement/compensation.

Unless the delivery method you select contains the word ‘Guaranteed’, the delivery service is not guaranteed. For example – ‘Next-Day Delivery with DPD Courier’ is not guaranteed next-day delivery, and no compensation or refund is provided if the delivery guideline from the carrier is not met. If you select a guaranteed delivery service, and you do not receive the delivery within the delivery guideline after it has been dispatched, you are entitled to a full refund of the delivery cost.

The delivery guidelines for the services are below:

DHL Global Mail by Deutsche Post within Netherlands = 2-3 working days

DHL Global Mail by Deutsche Post within EU = 3-7 working days, depends on country

DPD Home Delivery within Netherlands = 1 working day

DPD Home Delivery within EU = 2-7 working days, depends on country.

DHL Express Courier within Netherlands = 1 working day, guaranteed.

DHL Express Courier within EU = 1-3 working days, depends on country.

We retain proof of postage at all times.

Shipping Issues, Delays, Lost Parcels etc.

At MandiMart we pride ourselves on our same-day dispatch and fast delivery. We are constantly on the lookout for ways to improve our delivery service and avoid delays for our customers.

It is your responsibility as the customer to ensure you have entered the correct shipping address. When you place an order, you will be sent a confirmation email confirming your order details. Your address and the product details are included in the order details; this is your opportunity to correct any possible mistakes with your order. If you become aware of errors with your order, please make us aware at the earliest possible time by sending an email to MandiMartLimited@gmail.com. We will endeavour to alter your order before it is dispatched. Unfortunately, if your order has already been packed and labelled at our warehouse, we cannot affect it in any way. We cannot be held responsible for any issues that arise due to the incorrect information you have provided.

While we try our absolute best to minimise any shipping errors, we are only human. In the event we have sent you the wrong product, we believe that we have caused enough inconvenience through our mistake, and as a result of this we will dispatch the correct product to you at the next available opportunity, irrespective of whether or not you have returned the incorrect product at that moment. However, we do ask that you return the incorrect product promptly, but at your leisure. Failure to return the incorrect products will incur an invoice and subsequently debt collection as required. 

If you have not received your order after the expected delivery guideline has passed, please contact your local post/delivery office, and quote your tracking number to them. In 90+% of cases a ‘failed delivery attempt’ has been made but the postman didn’t leave a card to let you know this. If the parcel is indeed at the local delivery office you will be able to re-arrange delivery or collection of your parcel via an online portal on the carrier’s website, or by contacting the local delivery office directly.

Unfortunately, we are not able to guarantee delivery or the time/date that our carrier will plan to make the delivery – this is out of our control. If you parcel is delayed or lost you can rest assured that we will do everything in our power to help you trace your lost parcel. This will include following up tracking numbers and contacting carriers for further clarification if the tracking information is not explicit. MandiMart cannot accept responsibility for delays or losses caused by carriers until the ‘claims waiting time’ has expired. Until this has happened the only message we will receive from carriers is to wait. After this time, we are more than happy to begin a complaint/claim against the carrier for the delay/loss of your parcel.

If you have entered a ‘SafePlace’ for your parcel to be left (i.e. when you are not present to accept the delivery) and the carrier states that they have left the parcel in the specified ‘SafePlace’, then MandiMart cannot be held responsible for any losses that you have experienced through using the ‘SafePlace’ service.

Returns

We understand that your supplement requirements are subject to change and, as such, you may occasionally need to return unused/no longer prescribed products. We offer a ‘no contest’ return policy if the product is in reasonable expiry date, in its original condition, unopened with the security seal still in place and the return is initiated within 90 days of the order being placed. If it has been longer than 90 days, send an email and we will decide this on a case-by-case basis.

We will process a refund once we have received the returned product, and inspected its condition. MandiMart accepts no responsibility for returns that are lost or damaged en route to our address. For this reason, we strongly recommend using a tracked/registered service and ensuring the products are adequately protected, as required.

MandiMart cannot accept opened, unsealed products for return in any situation other than a (possible) manufacturing defect. In this situation we require the product to be returned to us and then we will converse with our supplier/manufacturer as to whether a manufacturing defect is present in the product. This could include returning the product to our supplier/manufacturer. If a manufacturing defect is present then you will be issued a new product replacement or a refund, whichever you should prefer. Please note that the return shipping is to be paid by customer and only on discovery of a manufacturing defect will this be refunded. If there is no manufacturing defect present you will not be refunded nor will a replacement be sent to you.

While we continually strive for perfection, we are only human and mistakes will happen from time to time. If we have mistakenly sent you the wrong product, we are more than happy to cover the cost of returning this wrong product to us. We believe that you have been inconvenienced enough through no fault of your own, and as such should not have to pay for the return, or wait until the initial product is returned before the correct product is dispatched. We will immediately dispatch the correct product for you, with no regard to whether we have received your product return. However, in the instance that you have ordered the wrong product or no longer require the product you have ordered, we would expect you to fund the return yourself.

These conditions do not affect your statutory rights.