Selenium is an essential trace mineral found in Brazil nuts ( 544 mcg per ounce !) sunflower seeds, fish and poultry products , onions and grains. Plants do not require selenium and therefore the content of plant sources varies with the soil content. Brazil nuts are grown in selenium rich soil in Brazil. Selenium content of the body is estimated to be 3-6mg in individuals living in low selenium areas and 13 mg in those living in high selenium areas. It is found mainly in the liver and kidneys.
What does selenium do?
The major importance of selenium lies in its place in 25 selenium dependent enzymes called selenoproteins. 5 important selenoproteins are
1) Cellular glutathione peroxidase
2) Extracellular glutathione peroxidase
3) Phospholipid hydroperoxide glutathione peroxidase
4) Gastrointestinal glutathione peroxidase
5) Olfactory glutathione peroxidase
- Selenium contributes to the protection of cells from oxidative stress and the protection of DNA, proteins and lipids from oxidative damage. All the selenoproteins above are antioxidant enzymes which are able to reduce the damaging reactive oxygen species to harmless water and alcohols
- Selenium contributes to normal spermatogenesis. The phospholipid hydroperoxide glutathione peroxidase protects the sperm mitochondrial capsule from oxidative damage and is then involved in the formation of a structural protein required by the mature sperm. Another selenoprotein ( selenoprotein V) exists only in the testes and is also involved in spermatogenesis
- Selenium contributes to normal thyroid function. Selenium is required for 3 different selenium dependent iodotyronine deiodinase enzymes. Thyroxn (T4) is converted to Triiodotyronine (T3) by one or more of these selenium dependent enzymes. These three enzymes can both activate and inactivate thyroid hormones
- Selenium contributes to the normal function of the immune system. It appears to regulate the expression of cytokines, cell signalling molecules which are in charge of the immune response. Selenium deficiency is associated with impaired immune function.
Selenium contributes to the maintenance of normal hair and nails. Selenium deficiency can lead to weak hair and nails. Hair and nails are primarily composed of proteins and these proteins are dependent on seleno proteins for their healthy production. Hair follicles and nail beds are renewing structures composed of cells called keratinocytes and seloproteins are essential for normal keratinocyte function
Selenium compounds are also important to kill a fungus which can live on the scalp that can cause dry shedding skin fragments (dandruff)
Ten drops contains: 57.5 mcg Selenium
Ingredients: Purified water, Sodium Selenate.
Although selenium is an essential, important mineral, care should be taken not to exceed 200mcg per day for adults except on the advice of your practitioner, consult your practtioner for children. Although the mechanism of toxicity is uncertain it may be due to excess selenium inhibiting dehydrogenase enzymes
Vitamins E, B6 and copper have all been shown to be synergistic to selenium and
Vitamin A, C and K antagonistic
- Orders for products that are in stock are dispatched daily Monday – Friday.
- Orders placed before 3pm (CET) Monday – Friday will be dispatched the same day.
- Orders placed after 3pm (CET) Monday – Friday will be dispatched the next working day.
- As such, orders placed after 3pm (CET) on Friday will be dispatched the following Monday.
- Orders will not be dispatched on Bank Holidays (Netherlands) or Weekends.
We have access to a variety of shipping options, provided by Deutsche Post, DPD and DHL Courier. You will select your delivery preference at the checkout when you place the order. We will endeavour to use your preferred delivery service wherever possible, while reserving the right to use an alternative courier of our choice as we deem necessary, this would always be a delivery upgrade, and never a downgrade.
As standard, we are only using delivery services that include tracking and insurance against damage/loss. This means if your parcel doesn’t arrive, or is damaged on arrival, you are entitled to a refund/replacement. All you need to do is send us some pictures of the damage. If you prefer to use a cheaper delivery service without tracking and insurance we can provide this for you by request, but if the parcel doesn’t arrive, or is damaged on arrival then you are not entitled to any refund/replacement/compensation.
Unless the delivery method you select contains the word ‘Guaranteed’, the delivery service is not guaranteed. For example – ‘Next-Day Delivery with DPD Courier’ is not guaranteed next-day delivery, and no compensation or refund is provided if the delivery guideline from the carrier is not met. If you select a guaranteed delivery service, and you do not receive the delivery within the delivery guideline after it has been dispatched, you are entitled to a full refund of the delivery cost.
The delivery guidelines for the services are below:
DHL Global Mail by Deutsche Post within Netherlands = 2-3 working days
DHL Global Mail by Deutsche Post within EU = 3-7 working days, depends on country
DPD Home Delivery within Netherlands = 1 working day
DPD Home Delivery within EU = 2-7 working days, depends on country.
DHL Express Courier within Netherlands = 1 working day, guaranteed.
DHL Express Courier within EU = 1-3 working days, depends on country.
We retain proof of postage at all times.
Shipping Issues, Delays, Lost Parcels etc.
At MandiMart we pride ourselves on our same-day dispatch and fast delivery. We are constantly on the lookout for ways to improve our delivery service and avoid delays for our customers.
It is your responsibility as the customer to ensure you have entered the correct shipping address. When you place an order, you will be sent a confirmation email confirming your order details. Your address and the product details are included in the order details; this is your opportunity to correct any possible mistakes with your order. If you become aware of errors with your order, please make us aware at the earliest possible time by sending an email to MandiMartLimited@gmail.com. We will endeavour to alter your order before it is dispatched. Unfortunately, if your order has already been packed and labelled at our warehouse, we cannot affect it in any way. We cannot be held responsible for any issues that arise due to the incorrect information you have provided.
While we try our absolute best to minimise any shipping errors, we are only human. In the event we have sent you the wrong product, we believe that we have caused enough inconvenience through our mistake, and as a result of this we will dispatch the correct product to you at the next available opportunity, irrespective of whether or not you have returned the incorrect product at that moment. However, we do ask that you return the incorrect product promptly, but at your leisure. Failure to return the incorrect products will incur an invoice and subsequently debt collection as required.
If you have not received your order after the expected delivery guideline has passed, please contact your local post/delivery office, and quote your tracking number to them. In 90+% of cases a ‘failed delivery attempt’ has been made but the postman didn’t leave a card to let you know this. If the parcel is indeed at the local delivery office you will be able to re-arrange delivery or collection of your parcel via an online portal on the carrier’s website, or by contacting the local delivery office directly.
Unfortunately, we are not able to guarantee delivery or the time/date that our carrier will plan to make the delivery – this is out of our control. If you parcel is delayed or lost you can rest assured that we will do everything in our power to help you trace your lost parcel. This will include following up tracking numbers and contacting carriers for further clarification if the tracking information is not explicit. MandiMart cannot accept responsibility for delays or losses caused by carriers until the ‘claims waiting time’ has expired. Until this has happened the only message we will receive from carriers is to wait. After this time, we are more than happy to begin a complaint/claim against the carrier for the delay/loss of your parcel.
If you have entered a ‘SafePlace’ for your parcel to be left (i.e. when you are not present to accept the delivery) and the carrier states that they have left the parcel in the specified ‘SafePlace’, then MandiMart cannot be held responsible for any losses that you have experienced through using the ‘SafePlace’ service.
We understand that your supplement requirements are subject to change and, as such, you may occasionally need to return unused/no longer prescribed products. We offer a ‘no contest’ return policy if the product is in reasonable expiry date, in its original condition, unopened with the security seal still in place and the return is initiated within 90 days of the order being placed. If it has been longer than 90 days, send an email and we will decide this on a case-by-case basis.
We will process a refund once we have received the returned product, and inspected its condition. MandiMart accepts no responsibility for returns that are lost or damaged en route to our address. For this reason, we strongly recommend using a tracked/registered service and ensuring the products are adequately protected, as required.
MandiMart cannot accept opened, unsealed products for return in any situation other than a (possible) manufacturing defect. In this situation we require the product to be returned to us and then we will converse with our supplier/manufacturer as to whether a manufacturing defect is present in the product. This could include returning the product to our supplier/manufacturer. If a manufacturing defect is present then you will be issued a new product replacement or a refund, whichever you should prefer. Please note that the return shipping is to be paid by customer and only on discovery of a manufacturing defect will this be refunded. If there is no manufacturing defect present you will not be refunded nor will a replacement be sent to you.
While we continually strive for perfection, we are only human and mistakes will happen from time to time. If we have mistakenly sent you the wrong product, we are more than happy to cover the cost of returning this wrong product to us. We believe that you have been inconvenienced enough through no fault of your own, and as such should not have to pay for the return, or wait until the initial product is returned before the correct product is dispatched. We will immediately dispatch the correct product for you, with no regard to whether we have received your product return. However, in the instance that you have ordered the wrong product or no longer require the product you have ordered, we would expect you to fund the return yourself.
These conditions do not affect your statutory rights.