Methyl Folate Pro 66 Capsules

Our exclusive Methyl Folate Pro formula provides the two metabolically bioactive forms of folate. L-5- Methylfolate and Folinic Acid together with niacinamide deliver significant support to all areas of the folate methylation process. Bioactive folate is necessary for all cells to function normally but is especially important in the nervous system and immune system. Methylfolate is an important co-factor in the production of dopamine and serotonin while also being important in mitochondrial and detoxification support.

Elevated folic acid levels in the blood plasma can indicate poor methylation. This formula is also necessary for polymorphisms in the FOLR1/2, DHFR, MTHFD1, MTHFS and MTHFR genes.

Use this product in conjunction with either Methylation Complete Pro or Methylation Pro Topical to provide benefits such as cellular energy and detoxification, mood stabilization, immune function, and optimal cognitive function.

The typical indications for this product include but are not limited to:

• * Presence of Folate Receptor Autoantibodies
• *Homozygous (2 copies) MTHFR polymorphism
• *Development (ages 8-20)
• *Slow recovery from major neurological injuries
• *Moderate to severe autism spectrum issues
• *Poor recovery from traumatic injury

Features
Folinic acid (also known as Leucovorin) is a 5-formyl derivative of tetrahydrofolic acid. It is readily converted to other reduced folic acid derivatives (e.g., tetrahydrofolate), and, thus, has vitamin activity that is equivalent to that of folic acid.

5-MTHF (L-Methyl tetrahydrofolate) is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. Folate benefits cardiovascular health and nervous system function. Ordinary folic acid supplements may not deliver the full spectrum of effects. This is due to the fact that once ingested, not everyone converts the usual folic acid supplements to their biologically active form called 5-methyltetrahydrofolate (5-MTHF). Methyl Folate Plus provides 5-MTHF in its active form. Recent studies have shown that a significant portion of the population have genetic enzyme deficiencies which prevent the conversion by methylation of folate to 5-MTHF.

5-MTHF has been shown to be up to seven times more bioavailable than regular folic acid. This greater bioavailability is especially important in people who have a genetic enzyme deficiency since it requires no conversion to become metabolically active. 5-MTHF is able to cross the blood-brain barrier to enhance brain synthesis of acetylcholine the neurotransmitter associated with memory, which is especially important for people with cognitive difficulties and neuro-immune syndromes.


Frequently asked question: Is 5-MTHF the same as L-Methylfolate? 
It is. We use two types of MTHF, one stabilized with calcium and one stabilized with glucosamine (non-shellfish-derived). Both are synonymous with L-Methylfolate.

Special Considerations: People with MTHFR & FLOR SNPs benefit greatly from taking methylfolate. Always take Methyl B12 with methylfolate, as it is a needed cofactor in methylation.

Niacinamide does not cause flushing at any dose. However, it is readily converted to an enzyme called NADH that is needed for metabolism and energy production to support mitochondrial health. Unlike other vitamins, the body is able to make its own niacinamide using tryptophan as the raw material. Tryptophan is an amino acid the body also uses to make serotonin, a critical neurotransmitter for moods, sometimes referred to as the Òhappy brain chemical.Ó Since tryptophan is often in short supply in the body, taking niacinamide can help spare it and make more available for serotonin production. As a result, niacinamide has complex and supportive interactions with body and brain function as well as a wide range of benefits.

Vitamin B2 (Riboflavin-5-Phosphate) Riboflavin is critical for normal growth and repair. It is needed to facilitate normal reproduction, cell growth and repair, and development of tissues. The body utilizes vitamin B2 to keep tissue health and to help accelerate healing of injuries. Riboflavin acts to help the immune system to function properly by reinforcing the body's reserve of antibodies which guard against infection.

Along with other B Vitamins, Vitamin B2 helps protect the nervous system. It could be an essential component for optimal health.*

Directions: Take one capsule twice daily or as directed by your healthcare professional. Take this product with a methylation support product that includes methyl B12, a necessary cofactor for delivery.

Ingredients
 

Other Ingredients: rice flour, ascorbic palmitate, silicon dioxide, HPMC (vegetable capsule)

• Orders for products that are in stock are dispatched daily Monday – Friday.
• Orders placed before 3pm (CET) Monday – Friday will be dispatched the same day.
• Orders placed after 3pm (CET) Monday – Friday will be dispatched the next working day.
• As such, orders placed after 3pm (CET) on Friday will be dispatched the following Monday.
• Orders will not be dispatched on Bank Holidays (Netherlands) or Weekends.

Delivery

We have access to a variety of shipping options, provided by Deutsche Post, DPD and DHL Courier. You will select your delivery preference at the checkout when you place the order. We will endeavour to use your preferred delivery service wherever possible, while reserving the right to use an alternative courier of our choice as we deem necessary, this would always be a delivery upgrade, and never a downgrade.

As standard, we are only using delivery services that include tracking and insurance against damage/loss. This means if your parcel doesn’t arrive, or is damaged on arrival, you are entitled to a refund/replacement. All you need to do is send us some pictures of the damage. If you prefer to use a cheaper delivery service without tracking and insurance we can provide this for you by request, but if the parcel doesn’t arrive, or is damaged on arrival then you are not entitled to any refund/replacement/compensation.

Unless the delivery method you select contains the word ‘Guaranteed’, the delivery service is not guaranteed. For example – ‘Next-Day Delivery with DPD Courier’ is not guaranteed next-day delivery, and no compensation or refund is provided if the delivery guideline from the carrier is not met. If you select a guaranteed delivery service, and you do not receive the delivery within the delivery guideline after it has been dispatched, you are entitled to a full refund of the delivery cost.

The delivery guidelines for the services are below:

DHL Global Mail by Deutsche Post within Netherlands = 2-3 working days

DHL Global Mail by Deutsche Post within EU = 3-7 working days, depends on country

DPD Home Delivery within Netherlands = 1 working day

DPD Home Delivery within EU = 2-7 working days, depends on country.

DHL Express Courier within Netherlands = 1 working day, guaranteed.

DHL Express Courier within EU = 1-3 working days, depends on country.

We retain proof of postage at all times.

Shipping Issues, Delays, Lost Parcels etc.

At MandiMart we pride ourselves on our same-day dispatch and fast delivery. We are constantly on the lookout for ways to improve our delivery service and avoid delays for our customers.

It is your responsibility as the customer to ensure you have entered the correct shipping address. When you place an order, you will be sent a confirmation email confirming your order details. Your address and the product details are included in the order details; this is your opportunity to correct any possible mistakes with your order. If you become aware of errors with your order, please make us aware at the earliest possible time by sending an email to MandiMartLimited@gmail.com. We will endeavour to alter your order before it is dispatched. Unfortunately, if your order has already been packed and labelled at our warehouse, we cannot affect it in any way. We cannot be held responsible for any issues that arise due to the incorrect information you have provided.

While we try our absolute best to minimise any shipping errors, we are only human. In the event we have sent you the wrong product, we believe that we have caused enough inconvenience through our mistake, and as a result of this we will dispatch the correct product to you at the next available opportunity, irrespective of whether or not you have returned the incorrect product at that moment. However, we do ask that you return the incorrect product promptly, but at your leisure. Failure to return the incorrect products will incur an invoice and subsequently debt collection as required. 

If you have not received your order after the expected delivery guideline has passed, please contact your local post/delivery office, and quote your tracking number to them. In 90+% of cases a ‘failed delivery attempt’ has been made but the postman didn’t leave a card to let you know this. If the parcel is indeed at the local delivery office you will be able to re-arrange delivery or collection of your parcel via an online portal on the carrier’s website, or by contacting the local delivery office directly.

Unfortunately, we are not able to guarantee delivery or the time/date that our carrier will plan to make the delivery – this is out of our control. If you parcel is delayed or lost you can rest assured that we will do everything in our power to help you trace your lost parcel. This will include following up tracking numbers and contacting carriers for further clarification if the tracking information is not explicit. MandiMart cannot accept responsibility for delays or losses caused by carriers until the ‘claims waiting time’ has expired. Until this has happened the only message we will receive from carriers is to wait. After this time, we are more than happy to begin a complaint/claim against the carrier for the delay/loss of your parcel.

If you have entered a ‘SafePlace’ for your parcel to be left (i.e. when you are not present to accept the delivery) and the carrier states that they have left the parcel in the specified ‘SafePlace’, then MandiMart cannot be held responsible for any losses that you have experienced through using the ‘SafePlace’ service.

Returns

We understand that your supplement requirements are subject to change and, as such, you may occasionally need to return unused/no longer prescribed products. We offer a ‘no contest’ return policy if the product is in reasonable expiry date, in its original condition, unopened with the security seal still in place and the return is initiated within 90 days of the order being placed. If it has been longer than 90 days, send an email and we will decide this on a case-by-case basis.

We will process a refund once we have received the returned product, and inspected its condition. MandiMart accepts no responsibility for returns that are lost or damaged en route to our address. For this reason, we strongly recommend using a tracked/registered service and ensuring the products are adequately protected, as required.

MandiMart cannot accept opened, unsealed products for return in any situation other than a (possible) manufacturing defect. In this situation we require the product to be returned to us and then we will converse with our supplier/manufacturer as to whether a manufacturing defect is present in the product. This could include returning the product to our supplier/manufacturer. If a manufacturing defect is present then you will be issued a new product replacement or a refund, whichever you should prefer. Please note that the return shipping is to be paid by customer and only on discovery of a manufacturing defect will this be refunded. If there is no manufacturing defect present you will not be refunded nor will a replacement be sent to you.

While we continually strive for perfection, we are only human and mistakes will happen from time to time. If we have mistakenly sent you the wrong product, we are more than happy to cover the cost of returning this wrong product to us. We believe that you have been inconvenienced enough through no fault of your own, and as such should not have to pay for the return, or wait until the initial product is returned before the correct product is dispatched. We will immediately dispatch the correct product for you, with no regard to whether we have received your product return. However, in the instance that you have ordered the wrong product or no longer require the product you have ordered, we would expect you to fund the return yourself.

These conditions do not affect your statutory rights.